The "Let Me In" meme features comedian Eric Andre from a 2016 episode of "The Eric Andre Show." In a segment parodying political protests, Andre is seen shaking a fence and screaming "Let me in!" during the Democratic National Convention. The dramatic, exaggerated plea became a popular reaction image and GIF, symbolizing desperate attempts to gain access or inclusion. It's widely used to humorously depict situations where someone or something is eagerly trying to get into a place, event, or group. The meme's versatility and Andre's expressive performance contribute to its enduring popularity in internet culture.