The "Me and the Boys" meme features a 1960s Spider-Man cartoon image with Spider-Man villains: Vulture, Electro, and Green Goblin. Originating on Instagram in 2018, it humorously depicts nostalgic, mischievous scenarios among friends. The meme typically follows the format of "Me and the boys" followed by an activity, evoking shared childhood memories or exaggerated mischief. It captures a sense of camaraderie and playful rebellion, often highlighting absurd or mundane actions made humorous by the exaggerated expressions and retro cartoon style. Its popularity surged on platforms like Reddit, emphasizing collective nostalgia and humorous nostalgia for simpler times.